Greenpharma Extract Library™ - GPE

The Greenpharma extract library is a plant extract library which combines Greenpharma expertise in natural source products, and its knowledge in pharmacognosy to create a unique source of diverse and original extracts for screening and lead discovery.
The GPE includes know-how in ethnobotany, botany, pharmacology, pharmacognosy, organic chemistry and analytical chemistry to present a variety of extracts as wide as possible. The selection procedure is based on biotope and taxonomic diversity. Moreover, a “patentability” criteria is added to ensure the originality of the selected plants. Each plant is stocked so that resupply is possible within a short delay.

Applications: hit & lead discovery, botanicals discovery.

GPE is presented in a format suitable for HTS. A microplate of extracts is made of 96 wells, 80 of which are filled with products. The columns A01-H01 and A12-H12 are empty. These columns are often used as controls in HTS procedures. Each of the 80 wells contains 2 mg of extract diluted in 200 µL of DMSO. This high concentration easily allows dilutions in order to avoid the side toxicity effect of DMSO. A GPE microplate contains 20 plants, each of them being represented by 4 different polarity solvent extracts.

CD-ROM
The CD-ROM supplied with the extract library contains the corresponding database named GPEDB developed with ACCESS 2000. This database describes the content of each well and includes information about the plant family, genus, species, organ and ethnobotanic data.

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